Neutrophil Oxidative Burst
Order Name
NOB
Test Number: None
Revision Date 02/20/2024
Test Number: None
Revision Date 02/20/2024
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Neutrophil Oxidative Burst
|
Flow cytometry |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 5mL | Whole Blood | Sodium Heparin (Green Top / No-Gel) | Room Temperature |
| Instructions | Order STAT Order using New Test Misc Use Labcorp test number 805245 Collect Monday through Wednesday Collect between 11am and 2pm send in STAT - Speciomen must be received at the lab by 3pm. Collect whole blood, green (Sodium Heparin) tube. Send a whole blood Sodium Heparin in the original tube Notify lab personnel prior to collection, Dr. Miller at 918-409-6645 Stability: Room temperature - 24 hours; Frozen-Unacceptable |
|||
| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Collect Monday through Wednesday |
| Expected TAT | 2-3 business days |
| Clinical Use | Patients with chronic granulomatous disease (CGD) have an inherited primary immunodeficiency with recurrent infections and granulomas. Their neutrophils are fully capable of ingesting bacteria and fungi but cannot kill because of the dysfunction of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system and thus an inability to produce superoxide anions required for killing of the bacteria and fungal organisms. The DHR flow assay provides an assessment of the reactive oxygen intermediate (ROI) production by measuring the NADPH oxidase activity. |
| Performing Labcorp Test Code | 805245 |
| Notes | Labcorp test code: 805245 Testing referred to Eurofins Viracor This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration |
| CPT Code(s) | 82657 |
| Lab Section | Reference Lab |