Peroxisomal (C22-C-26) Fatty Acid Profile, Serum
Order Name
Peroxisomal FA
Test Number: 6905961
Revision Date 09/25/2019
Test Number: 6905961
Revision Date 09/25/2019
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Peroxisomal (C22-C-26) Fatty Acid Profile, Serum
|
Gas Chromatography/Mass Spectrometry (GC/MS) |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 3 mL (1 mL) | Plasma | EDTA (Lavender Top) | Room Temperature |
| Instructions | Specimen Type: Lavender-top (EDTA) tube, gel-barrier tube or green-top (heparin) tube Specimen Storage: Maintain specimen at room temperature Special Instructions: Testing referred to Kennedy Krieger Lab K@#- This test should not be used by New York residents. |
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| GENERAL INFORMATION | |
|---|---|
| Clinical Use | Peroxisomes play a vital role in several metabolic pathways, including the synthesis of plasmalogens and bile acids. They are also involved in the catabolism of Very Long Chain Fatty Acids (VLCFAs), phytanic acid, and pristanic acid. Defects in these pathways usually result in the accumulation in tissues and body fluids of one or more metabolites derived from the blocked metabolic steps. Specific accumulations are used for the differential biochemical diagnosis of numerous peroxisomal disorders. These disorders include (A) Zellweger spectrum disorders of peroxisomal biogenesis, (B) X-linked adrenoleukodystrophy (X-ALD) and its adult form X-linked adrenomyeloneuropathy (X-AMN), (C) Refsum disease (Phytanoyl-CoA hydroxylase Deficiency), and (D) 2-methylacyl-CoA racemase deficiency |
| Performing Labcorp Test Code | 831503 |
| Notes | Labcorp Test Code: 831503 |
| CPT Code(s) | 82726 |
| Lab Section | Reference Lab |