Neuromyelitis Optica (NMO) Antibody (Aquaporin-4 Receptor)
Order Name
NMO AB
Test Number: 3805377
Revision Date 06/30/2023
Test Number: 3805377
Revision Date 06/30/2023
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Neuromyelitis Optica (NMO) Antibody (Aquaporin-4 Receptor)
|
Enzyme-Linked Immunosorbent Assay (ELISA) | 68548-7 |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 1 mL (0.2 mL) | Serum | Clot Activator SST | Refrigerated |
| Instructions | Specimen Type: Red-top tube OR gel-barrier tube Specimen Storage: Refrigerate Specimen Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube. Specimen Stability: Ambient: 24 hours, Refrigerated : 14 days, Frozen: 14 days |
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| GENERAL INFORMATION | |
|---|---|
| Expected TAT | 3 - 5 days |
| Clinical Use | Approximately 75 percent of patients with neuromyelitis optica (NMO) express antibodies to the aquaporin-4 (AQP4) receptor. Diagnosis of NMO requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis. While absence of antibodies to the AQP4 receptor does not rule out the diagnosis of NMO, presence of this antibody is diagnostic for NMO. |
| Performing Labcorp Test Code | 004210 |
| Notes | Labcorp Test Code: 004210 |
| CPT Code(s) | 86051 |
| Lab Section | Reference Lab |