Voltage-Gated Calcium Channel (VGCC) Antibody Assay
Order Name
CALCHANIGG
Test Number: 5502375
Revision Date 12/12/2022
Test Number: 5502375
Revision Date 12/12/2022
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Voltage-Gated Calcium Channel (VGCC) Antibody Assay
|
Quantitative Radioimmunoassay | 31024-3 |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 1 mL (0.4) | Serum | Clot Activator SST | Refrigerated |
| Alternate 1 | 1 mL (0.4) | Serum | Clot Activator (Red Top, No-Gel) | Refrigerated |
| Instructions | Notes: 0.4 mL (Note: This volume Does NOT allow for repeat testing.) Specimen Type: Red-top tube or gel-barrier tube Specimen Storage: Room temperature Specimen Collection: Serum should be separated from cells within one hour and transferred to a plastic transport tube. Specimen Stability: Ambient: 14 days, Refrigerated : 14 days, Frozen: 14 days |
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| GENERAL INFORMATION | |
|---|---|
| Expected TAT | 3 - 8 days |
| Clinical Use | Voltage-gated calcium channel (VGCC) autoantibodies are characteristic of Lambert-Eaton Myasthenic Syndrome (LEMS) with or without small-cell lung cancer. VGCC autoantibodies are also found, albeit less frequently and generally in low amounts, in paraneoplastic disease associated with lung, ovarian or breast carcinomas; in carcinomas (without LEMS or other paraneoplastic syndrome) and occasionally in neurological diseases such as amyotrophic lateral sclerosis (frequency of ~23%). |
| Performing Labcorp Test Code | 140640 |
| Notes | Labcorp Test Code: 140640 |
| CPT Code(s) | 86596 |
| Lab Section | Reference Lab |