Protein S, Functional
Order Name
PROT S FUN
Test Number: 1506100
Revision Date 10/08/2024
Test Number: 1506100
Revision Date 10/08/2024
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Protein S, Functional
|
Clot Detection | 27822-6 |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 5.4 mL | Whole Blood | Sodium Citrate 3.2% (Blue Top) | Room Temperature |
| Alternate 1 | 3.0 mL | Double Spun Plasma | Sterile, Capped Plastic Tube | Frozen |
| Instructions | Please indicate anticoagulant therapy. Collect Two 2.7mL Sodium Citrate 3.2% (Blue Top) tubes. Each 2.7mL Sodium Citrate 3.2% (Blue Top) tube must be filled to the proper level, no hemolysis. Improperly filled tubes can give erroneous results. Whole blood must be transported to lab immediately. If testing cannot be started within 4 hours of collection the specimen must be double spun then 1.5mL plasma aliquot from each tube into individual plastic aliquot tubes and freeze. Do not pool aliquots together! |
|||
| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Tue |
| Expected TAT | 1-7 Days |
| Clinical Use | Protein S has an essential anticoagulant function. A congenital or acquired deficiency of Protein S increases the risk of thrombo-embolism. Congenital deficiencies are divided into 3 types, based on levels of both total and free Protein S Antigen, and on the activity level of Protein S. Protein S can also be decreased in hepatic disorders, inflammatory syndromes and oral anticoagulant therapy. |
| CPT Code(s) | 85306 |
| Lab Section | Coagulation |