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Neuromyelitis Optica (NMO) Antibody (Aquaporin-4 Receptor)

Order Name NMO AB
Test Number: 3805377
Revision Date 01/01/2022
Test Name Methodology LOINC Code
Neuromyelitis Optica (NMO) Antibody (Aquaporin-4 Receptor)
Semi-Quantitative Enzyme-Linked Immunosorbent Assay 61430-5 
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 1 mL (0.3 mL) Serum Clot Activator SST Refrigerated
Instructions Separate serum from cells ASAP or within 2 hours of collection.
GENERAL INFORMATION
Testing Schedule Tues, Thur 
Expected TAT 1-6 days after set-up  
Clinical Use Approximately 75 percent of patients with neuromyelitis optica (NMO) express antibodies to the aquaporin-4 (AQP4) receptor. Diagnosis of NMO requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis. While absence of antibodies to the AQP4 receptor does not rule out the diagnosis of NMO, presence of this antibody is diagnostic for NMO. 
Notes Reference Lab: ARUP
Test Code: 2003036
Click Here to view information on the ARUP website.
CPT Code(s) 86051
Lab Section Reference Lab