Neuromyelitis Optica (NMO) Antibody (Aquaporin-4 Receptor)
Order Name
NMO AB
Test Number: 3805377
Revision Date 01/01/2022
Test Number: 3805377
Revision Date 01/01/2022
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Neuromyelitis Optica (NMO) Antibody (Aquaporin-4 Receptor)
|
Semi-Quantitative Enzyme-Linked Immunosorbent Assay | 61430-5 |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 1 mL (0.3 mL) | Serum | Clot Activator SST | Refrigerated |
| Instructions | Separate serum from cells ASAP or within 2 hours of collection. | |||
| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Tues, Thur |
| Expected TAT | 1-6 days after set-up |
| Clinical Use | Approximately 75 percent of patients with neuromyelitis optica (NMO) express antibodies to the aquaporin-4 (AQP4) receptor. Diagnosis of NMO requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis. While absence of antibodies to the AQP4 receptor does not rule out the diagnosis of NMO, presence of this antibody is diagnostic for NMO. |
| Notes | Reference Lab: ARUP Test Code: 2003036 Click Here to view information on the ARUP website. |
| CPT Code(s) | 86051 |
| Lab Section | Reference Lab |