Neisseria Meningitidis IgG Vaccine Response
Order Name
NEIS M VAC
Test Number: 5513425
Revision Date 02/22/2022
Test Number: 5513425
Revision Date 02/22/2022
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Neisseria meningitidis Serogroup A IgG
|
Quantitative Multiplex Bead Assay | 28546-0 |
|
Neisseria meningitidis Serogroup C IgG
|
Quantitative Multiplex Bead Assay | 28547-8 |
|
Neisseria meningitidis Serogroup Y IgG
|
Quantitative Multiplex Bead Assay | 60466-0 |
|
Neisseria meningitidis Serogroup W-135 IgG
|
Quantitative Multiplex Bead Assay | 60465-2 |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 1mL (0.25) | Serum | Clot Activator SST | Refrigerated |
| Instructions | Collect: Serum separator tube. Postimmunization specimen should be drawn 30 days after immunization and, if shipped separately, must be received within 60 days of preimmunization specimen. Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum to an Serum separator tube. (Min: 0.25 mL). MARK SPECIMENS CLEARLY AS PRE- OR POSTPNEUMOCOCCAL VACCINE SO SPECIMENS WILL BE SAVED AND TESTED SIMULTANEOUSLY. Storage/Transport Temperature: Refrigerated. Pre- and postpneumococcal vaccine specimens can be submitted separately or together for testing. Unacceptable Conditions: Plasma or other body fluids. Contaminated, hemolyzed or severely lipemic specimens Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year |
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| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | MonOnce a week, volume dependant. |
| Expected TAT | 1-8 days |
| Clinical Use | This assay measures serum IgG antibodies recognizing polysaccharide antigens from the four Neisseria meningitidis serogroups included in the licensed meningococcal vaccine. The meningococcal vaccine response is best evaluated by testing pre-vaccination and post-vaccination samples in parallel. A two-fold or greater increase for at least two serogroups is expected when comparing post-vaccination to pre-vaccination results. N. meningitidis IgG levels peak approximately one month post-vaccination, but decline markedly by two years. |
| Notes | Testing includes the following Serogroups: Serogroup A, Serogroup C, Serogroup Y and Serogroup W-135. Reference Lab: ARUP Test Code: 2001603 Click Here to view information on the ARUP website. |
| CPT Code(s) | 86741x4 |
| Lab Section | Reference Lab |