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Anti-Neutrophil Cytoplasmic Antibody (ANCA)

Order Name NEUT CY AB
Test Number: 5565200
Revision Date 01/01/2022
Test Name Methodology LOINC Code
Anti-Neutrophil Cytoplasm Titer
Indirect Fluorescent Antibody 17351-8 
Anti-Neutrophil Cytoplasmic Pattern
Indirect Fluorescent Antibody 49308-0 
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 1 mL Serum Clot Activator SST Refrigerated or Frozen
Instructions Stability/Storage: Room Temperature: N/A, Refrigerated(2-8C): 48 hours, Frozen(-20C): 90 Days.
GENERAL INFORMATION
Testing Schedule Mon - Fri 
Expected TAT 3 Days  
Clinical Use ANCA is a family of autoantibodies with varied specificities. The 2 types of ANCA patterns are C- and P. C- and P- ANCA can be of considerable value in the diagnosis of the spectrum of vasculitis (e.g. Wegener's). Positive ANCA results presenting C-ANCA and P-ANCA will reflex to specific testing for MPO and/or PR-3 antibodies. An Atypical-P ANCA is associated with inflammatory bowel disease and will not reflex to MPO and/or PR-3 testing. 
CPT Code(s) 86036
Lab Section Immunology - Serology