Chronic Urticaria PD-BATC
Order Name
CU INDEX
Test Number: 5587555
Revision Date 06/03/2025
Test Number: 5587555
Revision Date 06/03/2025
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Chronic Urticaria PD-BATC
|
Flow cytometry | 75023-2 |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 1 mL (0.5 mL) | Serum | Clot Activator (SST or Red No-Gel) | Frozen |
| Instructions | Specimen: Serum 1 mL (0.5 mL Minimum Volume: 0.5 mL (Note: This volume does not allow for repeat testing.) Container: Gel-barrier tube or red-top tube Collection: Allow to clot then Transfer separated serum to a plastic transport tube and Freeze. Storage Requirements:Frozen Stability Requirements: Room temperature 1 day, Refrigerated 14 days, Frozen 2 months (Freeze/thaw cycles Stable x3) Cause for Rejection: Specimen that are inadequately labeled, lipemic, hemolyzed, cloudy or microbiologically contaminated. |
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| GENERAL INFORMATION | |
|---|---|
| Expected TAT | 7 - 10 days |
| Clinical Use | Chronic Urticaria - Pooled Donor Basophil Activation Testing (PD-BAT) |
| CPT Code(s) | 86849 |
| Internal Comments | 10/17/17 link - JK 3/1/17 tat update - JK 11/13/18 - Test name update; synonyms added - ticket # 650249 (SN) 6/3/25 changed from Chronic Urticaria Index to Chronic Urticaria - Pooled Donor Basophil Activation Testing (PD-BAT) Labcorp Test Code: from 820022 to 505800 CPT from 86352 to 86352 Patients with a chronic form of urticaria who are positive (> 10) with the CU index® have an autoimmune basis for their disease. A positive result does not indicate which autoantibody (anti-IgE, anti-FceRI or anti-FceRII) is present. Ex-Vivo Challenge and cell culture: Donor blood cells are incubated with patient serum, a negative control and a positive control. Following the ex-vivo challenge, the cells are centrifuged and the supernatant is recovered for assay of histamine released. Histamine Analysis: Using a quantitative enzyme immunoassay, the histamine released into the supernatant is measured and compared to the total histamine in the basophils. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration. |
| Lab Section | Reference Lab |