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Regional Medical Lab
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Index:

PIK3CA Mutation Analysis

Order Name PIK3CA Mutat
Test Number: 6907417
Revision Date 01/19/2021
Test Name Methodology LOINC Code
PIK3CA Mutation Analysis
Polymerase Chain Reaction/Sequencing 60034-6 
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 1 Block Tissue Paraffin Block Ambient / Refrigerated
Instructions Preferred Specimen: FFPE Block

Acceptable
5mL (3mL) whole blood or 3mL (1mL) bone marrow aspirate collected in an EDTA (Lav) or NaHep (Drk Grn) tube
or
8 (min 4) unstained charged (+) slides

Do not reject specimens, send to laboratory for screening.

Stability: 
FFPE block or unstained slides: Ambient / Refrigerated - 5 yrs; Frozen - Unacceptable
Whole blood or Bone marrow: Ambient / Refrigerated - 72 hours; Frozen - Unacceptable
GENERAL INFORMATION
Testing Schedule Daily 
Expected TAT 7 days from setup  
Clinical Use PIK3CA Mutation Analysis - PIK3CA mutation has been associated with poor prognosis in endometrial, breast and colorectal cancers. Mutations in exons 9 and 20 of PIK3CA ave also been associated with resistance to cetuximab therapy in patients with colorectal cancer. 
Notes Reference Lab: Quest
Test Code: 16897
Click Here to view information on the Quest website.
CPT Code(s) 81404
Lab Section Reference Lab