PIK3CA Mutation Analysis
Order Name
PIK3CA Mutat
Test Number: 6907417
Revision Date 01/19/2021
Test Number: 6907417
Revision Date 01/19/2021
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
PIK3CA Mutation Analysis
|
Polymerase Chain Reaction/Sequencing | 60034-6 |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 1 Block | Tissue | Paraffin Block | Ambient / Refrigerated |
| Instructions | Preferred Specimen: FFPE Block Acceptable: 5mL (3mL) whole blood or 3mL (1mL) bone marrow aspirate collected in an EDTA (Lav) or NaHep (Drk Grn) tube or 8 (min 4) unstained charged (+) slides Do not reject specimens, send to laboratory for screening. Stability: FFPE block or unstained slides: Ambient / Refrigerated - 5 yrs; Frozen - Unacceptable Whole blood or Bone marrow: Ambient / Refrigerated - 72 hours; Frozen - Unacceptable |
|||
| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Daily |
| Expected TAT | 7 days from setup |
| Clinical Use | PIK3CA Mutation Analysis - PIK3CA mutation has been associated with poor prognosis in endometrial, breast and colorectal cancers. Mutations in exons 9 and 20 of PIK3CA ave also been associated with resistance to cetuximab therapy in patients with colorectal cancer. |
| Notes | Reference Lab: Quest Test Code: 16897 Click Here to view information on the Quest website. |
| CPT Code(s) | 81404 |
| Lab Section | Reference Lab |