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Test Directory


Metanephrines, Plasma (Free)

Test Number: 3805327
Revision Date 02/16/2021
Test Name Methodology LOINC Code
Metanephrine, Free
Quant Liquid Chromatography-Tandem Mass Spectrometry 25474-8 
Normetanephrine, Free
Quant Liquid Chromatography-Tandem Mass Spectrometry 25489-6 
Metanephrines Interpretation
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 2 mL (1 mL) Plasma EDTA (Lavender Top) Frozen
Alternate 1 2 mL (1 mL) Plasma Dark Green No-Gel Heparin (Na or Li) Frozen
Instructions Process Plasma Specimen to Frozen Aliquot ASAP.
Separate the plasma within 1 hour of venipuncture. After centrifugation, 2mL(1mL) plasma should be transferred to a plastic, leak-proof Aliquot vial and frozen for immediately.
Stability After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month
Unacceptable specimens: Plasma separator tubes. Body fluids other than EDTA or heparinized plasma. Non-frozen specimens. Grossly hemolyzed. 

Patient Preparation: Drugs and medications may affect results and should be discontinued for at least 72 hours prior to specimen collection, if possible. Collection of the specimen after the patient has rested for 15 minutes in a supine position is recommended.
Testing Schedule Sun-Sat 
Expected TAT 3-5 Days  
Notes Many drugs/medications, including over-the-counter and herbal products, can interfere with test results. Testing for all potential interactions is not possible. If the patient is taking a drug not listed as an interferent, its potential effect on test results is unknown. If test results are inconsistent with clinical evidence, drug interference should be considered. If appropriate, the patient should discontinue the potential interferent for 48-72 hours and a new sample collected for retesting.
CPT Code(s) 83835
Lab Section Reference Lab